abstract：:"Pulmonary Interstitial Glycogenosis: Diagnostic Evaluation and Clinical Course," written by Liptzin et al is a timely and insightful phenotypic summary of a rare pediatric interstitial lung disease. Twenty-four infants with biopsy-proven pulmonary interstitial glycogenosis (PIG) were reviewed at their center. Genetic...

journal_title：Pediatric pulmonology

authors： Yonker LM,Kinane TB

更新日期：2018-12-01 00:00:00

abstract：:Background The prevalence of respiratory-technology dependent children is increasing although for most children the goal is liberation from technology. Liberation from home mechanical ventilation (HMV) and decannulation strategies vary due to the lack of clinical practice standards. The primary objective of this study...

journal_title：Pediatric pulmonology

authors： Bashir A,Henningfeld JK,Thompson NE,D'Andrea LA

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:In this cohort study spanning an 18-year period, we evaluated the prevalence and associated mortality rate of epidemic strains of pseudomonas aeruginosa (PsA), especially Australian Epidemic Strain Type 1 (AES1), in a pediatric cystic fibrosis center practicing cohort segregation and early PsA eradication....

journal_title：Pediatric pulmonology

authors： Kevat A,Carzino R,Massie J,Harrison J,Griffiths AL

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Percutaneous lymphatic intervention (PCL) is a promising new therapy for plastic bronchitis (PB). We characterized bronchoalveolar lavage (BAL) and cast morphology in surgically repaired congenital heart disease (CHD) patients with PB during PCL. We quantified respiratory and bronchoscopic characteristics an...

journal_title：Pediatric pulmonology

authors： Geanacopoulos AT,Savla JJ,Pogoriler J,Piccione J,Phinizy P,DeWitt AG,Blinder JJ,Pinto E,Itkin M,Dori Y,Goldfarb SB

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Acute bronchiolitis is a major cause of acute respiratory distress in infants. The soluble receptor for advanced glycation end-products (sRAGE) is a biomarker of pulmonary damage processes, with a diagnostic and a prognostic value in acute respiratory distress syndrome (ARDS). The RAGE pathway is also impl...

journal_title：Pediatric pulmonology

authors： Egron C,Roszyk L,Rochette E,Jabaudon M,Sapin V,Mulliez A,Labbé A,Coste K

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Chest computerized tomography (CT) scores are associated with the frequency of future pulmonary exacerbations in people with cystic fibrosis (CF). However, cut-off values to identify children with mild lung disease with different risks for frequent future pulmonary exacerbations have not been identified. ME...

journal_title：Pediatric pulmonology

authors： Sanders DB,Li Z,Parker-McGill K,Farrell P,Brody AS

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Pulmonary function testing is commonly performed for diagnosis and clinical management of respiratory diseases. It is important to use appropriate reference equations from healthy subjects for interpretation of data from infants with lung disease. This study aimed to determine if published reference equation...

journal_title：Pediatric pulmonology

authors： Lu Z,Foong RE,Kowalik K,Moraes TJ,Dubeau A,Lefebvre D,Davis SD,Balkovec S,Becker A,Mandhane P,Turvey SE,Lou W,Sears MR,Ratjen F,Subbarao P

更新日期：2018-07-01 00:00:00

abstract：AIM:Magnesium is an adjunctive therapy used in patients with status asthmaticus who do not respond to conventional therapy. The optimal time from initiation of therapy, to determination of response and administration of magnesium has not yet been resolved. Our objective was to determine if magnesium administered in the...

journal_title：Pediatric pulmonology

authors： DeSanti RL,Agasthya N,Hunter K,Hussain MJ

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Laryngomalacia is the most prevalent cause of congenital stridor. Flexible laryngobronchoscopy (FLB) is the gold standard for diagnosis. However, FLB requires venous access, deep sedation or general anesthesia, and is associated with patient's and parental discomfort and a considerable cost. Laryngeal ultr...

journal_title：Pediatric pulmonology

authors： Friedman S,Sadot E,Gut G,Armoni Domany K,Sivan Y

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Swallowing disorders which lead to aspiration are common in premature infants with a postmenstrual age (PMA) of >36 weeks. Aspiration is often silent and the unique symptom is desaturation during feeding. The aim of this study was 1) to determine the number of prematures with desaturations during feeding due...

journal_title：Pediatric pulmonology

authors： Vetter-Laracy S,Osona B,Roca A,Peña-Zarza JA,Gil JA,Figuerola J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Our therapeutic approach to a habit/tic cough is simple reassurance in a single consultation. To quality assure our practice, we followed up children to determine outcomes at least 3 months after diagnosis. DESIGN:Consecutive children diagnosed over 6 years were studied. Medical records were analyzed retros...

journal_title：Pediatric pulmonology

authors： Wright MFA,Balfour-Lynn IM

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Medication adherence among adolescents with cystic fibrosis (CF) is often suboptimal and this has significant impact on their health and quality of life. The purpose of the study was to evaluate the impact of frequent home pulmonary function (PFT) monitoring on medication adherence among adolescents with CF. ...

journal_title：Pediatric pulmonology

authors： Shakkottai A,Kaciroti N,Kasmikha L,Nasr SZ

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Extremely low gestational age neonates (ELGANs) are at risk for pulmonary hypertension (PH). We hypothesized that PH, defined by echocardiogram at 36 weeks gestational age (GA), would associate with respiratory morbidity, increased oxidant stress, and reduced nitric oxide production. STUDY DESIGN:ELGANs in t...

journal_title：Pediatric pulmonology

authors： O'Connor MG,Suthar D,Vera K,Slaughter JC,Maitre NL,Steele S,Beller A,Fike CD,Aschner JL,Moore PE,Austin ED

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:This study was designed to establish a porcine model of reversible obstruction of endobronchial foreign body (FB) and to assess the natural pulmonary reexpansion process using radiology and histopathology after removal of the bronchial FB. METHODS:A metal stent was placed in the right lower lobe bronchial l...

journal_title：Pediatric pulmonology

authors： Wang S,Tu J,Song Y

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:The efficacy of nebulized hypertonic saline (HS) therapy for shortening hospital length of stay (LOS) or improving bronchiolitic symptoms remains controversial. Most studies enrolled small numbers of subjects and did not consider the role of respiratory syncytial virus (RSV), the most common cause of acute...

journal_title：Pediatric pulmonology

authors： Morikawa Y,Miura M,Furuhata MY,Morino S,Omori T,Otsuka M,Chiga M,Obonai T,Hataya H,Kaneko T,Ishikura K,Honda M,Hasegawa Y,Tokyo Pediatric Clinical Research Network.

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections worldwide, causing disproportionate morbidity and mortality in infants and children. Infants with stronger Th1 responses have less severe disease, yet little is known about the infant T-cell response within the air spa...

journal_title：Pediatric pulmonology

authors： Eichinger KM,Kosanovich JL,Empey KM

更新日期：2018-02-01 00:00:00

abstract：:Wheezing is the most widely reported adventitious lung sound in the English language. It is recognized by health professionals as well as by lay people, although often with a different meaning. Wheezing is an indicator of airway obstruction and therefore of interest particularly for the assessment of young children an...

journal_title：Pediatric pulmonology

authors： Pasterkamp H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Premature neonates frequently require oxygen supplementation as a therapeutic intervention that, while necessary, also exposes the lung to significant oxidant stress. We hypothesized that hyperoxia has a deleterious effect on alveolar epithelial barrier function rendering the neonatal lung susceptible to inj...

journal_title：Pediatric pulmonology

authors： Vyas-Read S,Vance RJ,Wang W,Colvocoresses-Dodds J,Brown LA,Koval M

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the contents of parent-created emergency tracheostomy kits and identify deficiencies. METHODS:This was an observational study. Data on emergency tracheostomy kits were abstracted for 30 consecutive children who had a tracheostomy tube in situ during an outpatient clinic visit with the Division of...

journal_title：Pediatric pulmonology

authors： Amin R,Zabih W,Syed F,Polyviou J,Tran T,Propst EJ,Holler T

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) is a major cause of childhood morbidity and mortality worldwide. The angiotensin-converting enzyme (ACE) gene is a potential candidate gene for CAP risk. OBJECTIVES:In this study, we aimed to investigate whether the ACE insertion/deletion (I/D) polymorphism (rs4340) could ...

journal_title：Pediatric pulmonology

authors： Abouzeid H,Alkholy UM,Abdou MA,Morsy SM,Abdelrahman HM,Sherif AM,Abdalmonem N,Hamed ME,Allah MAN,Al Morshedy S,Elashkar SSA,Noah MA,Hegab MS,Akeel NE,Hashem MIA,Gawish HH,Fattah LA

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:We assessed the performance of a tracheostomy decannulation protocol privileging safety over quickness, in pediatric patients undergoing rehabilitation from severe acquired brain injury. We analyzed factors associated with decannulation timing and possibility and examined cases of failure. HYPOTHESIS:A safe...

journal_title：Pediatric pulmonology

authors： Pozzi M,Galbiati S,Locatelli F,Clementi E,Strazzer S

更新日期：2017-11-01 00:00:00

abstract：:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their car...

journal_title：Pediatric pulmonology

authors： Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer D

更新日期：2017-11-01 00:00:00

abstract：:In this article, we describe existing CF registries with a focus on US registry data collected through the CF Foundation Patient Registry (CFFPR) and the Epidemiologic Study of CF (ESCF); highlight what registries have taught us regarding epidemiology of CF; showcase the impact of registries on research and clinical c...

journal_title：Pediatric pulmonology

authors： Fink AK,Loeffler DR,Marshall BC,Goss CH,Morgan WJ

更新日期：2017-11-01 00:00:00

abstract：:The autoimmune manifestations of primary immunodeficiencies, such as autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency (CVID), often constitute a great therapeutic challenge and have a significant impact on patients' morbidity and mortality. The most common autoimmune presentations ar...

journal_title：Pediatric pulmonology

authors： Bucciol G,Petrone A,Putti MC

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:Pediatric Pulmonology continues to publish research and clinical topics related to the entire range of children's respiratory disorders. As we have done annually in recent years, we here summarize some of the past year's publications in our major topic areas, as well as selected literature in these areas from other co...

journal_title：Pediatric pulmonology

authors： Auten R,Ren C,Yilmaz O,Noah TL

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Our objective was to obtain follow-up pulmonary function testing and assessment of clinical respiratory outcomes, at 1-2 years, in preterm infants whose mothers were randomized to a single rescue course of antenatal steroids (AS) versus placebo. METHODS:Follow-up of a randomized, double-blinded tr...

journal_title：Pediatric pulmonology

authors： McEvoy C,Schilling D,Spitale P,O'Malley J,Bowling S,Durand M

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To define the mortality and long-term outcomes of children undergoing tracheostomy. DESIGN:Retrospective chart and Texas Department of Health Bureau of Vital Statistics review of patients admitted to a Pediatric Intensive Care Unit who underwent a tracheostomy between 2001 and 2011. Mortality and decannulati...

journal_title：Pediatric pulmonology

authors： McPherson ML,Shekerdemian L,Goldsworthy M,Minard CG,Nelson CS,Stein F,Graf JM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Population-based studies investigating health-related quality of life (HRQoL) among asthmatic adolescents are rare. Further, among subjects with asthma, HRQoL may be affected by asthma control and severity. AIM:To investigate HRQoL in relation to asthma control and asthma severity among adolescents. METHOD...

journal_title：Pediatric pulmonology

authors： Stridsman C,Backman H,Eklund BM,Rönmark E,Hedman L

更新日期：2017-07-01 00:00:00

abstract：:To systematically review the clinical outcomes of surfactant administration via a thin endotracheal catheter during spontaneous breathing compared with conventional administration involving tracheal intubation, mechanical ventilation (MV), and tracheal extubation, in preterm infants. PubMed, EMBASE, and the Cochrane L...

journal_title：Pediatric pulmonology

authors： Wu W,Shi Y,Li F,Wen Z,Liu H

更新日期：2017-06-01 00:00:00

abstract：:Childhood interstitial lung disease (chILD) comprises a wide heterogeneous group of rare parenchymal lung disorders associated with substantial morbidity and mortality. Pulmonary hypertension is a common comorbidity in adults with interstitial lung disease (ILD) and associated with poor survival. We aimed to systemati...

journal_title：Pediatric pulmonology

authors： Bromley S,Vizcaya D

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases and modulation in animal models has therapeutic benefit. We hypothesise...

journal_title：Pediatric pulmonology

authors： Forrester DL,Barr HL,Fogarty A,Knox A

更新日期：2017-04-01 00:00:00

abstract：:Assessment of dynamic inspiratory function may provide valuable information about the degree and progression of pulmonary involvement in patients with Duchenne muscular dystrophy (DMD). The aims of this study were to characterize inspiratory function and to assess the efficacy of idebenone on this pulmonary function o...

journal_title：Pediatric pulmonology

authors： Buyse GM,Voit T,Schara U,Straathof CS,D'Angelo MG,Bernert G,Cuisset JM,Finkel RS,Goemans N,Rummey C,Leinonen M,Mayer OH,Spagnolo P,Meier T,McDonald CM,DELOS Study Group.

更新日期：2017-04-01 00:00:00

abstract：:Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a rare and severe side-effect, mainly described after intake of anticonvulsants, allopurinol, or antibiotics. It usually begins within 2 months after drug introduction. Symptoms include cutaneous rash, hematologic abnormalities, and internal orga...

journal_title：Pediatric pulmonology

authors： Gohy S,Froidure A,Lebecque P

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To validate the bronchiolitis score of Sant Joan de Déu (BROSJOD) and to examine the previously defined scoring cutoff. PATIENTS AND METHODS:Prospective, observational study. BROSJOD scoring was done by two independent physicians (at admission, 24 and 48 hr). Internal consistency of the score was assessed us...

journal_title：Pediatric pulmonology

authors： Balaguer M,Alejandre C,Vila D,Esteban E,Carrasco JL,Cambra FJ,Jordan I

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The prevalence of obstructive sleep apnea (OSA) is higher in children with poorly controlled asthma. We aimed to determine the validity of the Pediatric Sleep Questionnaire (PSQ) to screen for OSA in children with asthma. METHODS:This retrospective review encompassed sleep studies and medical records of asth...

journal_title：Pediatric pulmonology

authors： Ehsan Z,Kercsmar CM,Collins J,Simakajornboon N

更新日期：2017-03-01 00:00:00

abstract：:A neonate with severe neonatal asphyxia was treated with therapeutic hypothermia. He developed hypothermia-induced respiratory deterioration, after which congenital tracheal stenosis and pulmonary artery sling were diagnosed. Even low-grade hypothermia is likely to induce bronchial narrowing in neonates, especially in...

journal_title：Pediatric pulmonology

authors： Nakajima J,Sunohara D,Kawashima H

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:Induced sputum sampling holds promise as a method for obtaining samples representative of the lower airways in young children. Collection of induced sputum samples in young children differs from older children and adults' as pharyngeal suctioning is often required. Our aim was to determine the sensitivity ...

journal_title：Pediatric pulmonology

authors： D'Sylva P,Caudri D,Shaw N,Turkovic L,Douglas T,Bew J,Keil AD,Stick S,Schultz A

更新日期：2017-02-01 00:00:00